diff --git a/.azure-pipelines/macos.yml b/.azure-pipelines/macos.yml
deleted file mode 100644
index 9ad9edae8..000000000
--- a/.azure-pipelines/macos.yml
+++ /dev/null
@@ -1,11 +0,0 @@
-variables:
-  CI: true
-
-jobs:
-- template: jobs/test.yml
-  parameters:
-    vmImage: macos-10.14
-
-- template: jobs/package.yml
-  parameters:
-    vmImage: macos-10.14
diff --git a/.github/workflows/linting.yml b/.github/workflows/linting.yml
index 0ff16be64..ebe98fec7 100644
--- a/.github/workflows/linting.yml
+++ b/.github/workflows/linting.yml
@@ -19,7 +19,6 @@ jobs:
         os:
         - Ubuntu
         - Windows
-        - MacOS
 
     steps:
     - uses: actions/checkout@v2
diff --git a/.github/workflows/macos.yml b/.github/workflows/macos.yml
new file mode 100644
index 000000000..bdf3f671b
--- /dev/null
+++ b/.github/workflows/macos.yml
@@ -0,0 +1,129 @@
+name: MacOS
+
+on:
+  push:
+    branches:
+    - master
+  pull_request:
+  schedule:
+  # Run every Friday at 18:02 UTC
+  - cron: 2 18 * * 5
+
+jobs:
+  dev-tools:
+    name: Quality Check
+    runs-on: macos-latest
+
+    steps:
+    # Caches
+    - name: pip cache
+      uses: actions/cache@v1
+      with:
+        path: ~/.cache/pip
+        key: ${{ runner.os }}-pip-${{ hashFiles('tools/requirements/tests.txt') }}-${{ hashFiles('tools/requirements/docs.txt') }}-${{ hashFiles('tox.ini') }}
+        restore-keys: |
+          ${{ runner.os }}-pip-
+          ${{ runner.os }}-
+    - name: Set PY (for pre-commit cache)
+      run: echo "::set-env name=PY::$(python -c 'import hashlib, sys;print(hashlib.sha256(sys.version.encode()+sys.executable.encode()).hexdigest())')"
+    - name: pre-commit cache
+      uses: actions/cache@v1
+      with:
+        path: ~/.cache/pre-commit
+        key: pre-commit|2020-02-14|${{ env.PY }}|${{ hashFiles('.pre-commit-config.yaml') }}
+
+    # Setup
+    - uses: actions/checkout@v2
+    - name: Set up Python 3.8
+      uses: actions/setup-python@v2
+      with:
+        python-version: 3.8
+
+    - name: Install tox
+      run: python -m pip install tox
+
+    # Main check
+    - run: python -m tox -e "lint,docs"
+
+  packaging:
+    name: Packaging
+    runs-on: macos-latest
+
+    steps:
+    # Caches
+    - name: pip cache
+      uses: actions/cache@v1
+      with:
+        path: ~/.cache/pip
+        key: ${{ runner.os }}-pip-${{ hashFiles('tools/requirements/tests.txt') }}-${{ hashFiles('tools/requirements/docs.txt') }}-${{ hashFiles('tox.ini') }}
+        restore-keys: |
+          ${{ runner.os }}-pip-
+          ${{ runner.os }}-
+    # Setup
+    - name: Set up git credentials
+      run: |
+        git config --global user.email "pypa-dev@googlegroups.com"
+        git config --global user.name "pip"
+    - uses: actions/checkout@v2
+    - name: Set up Python 3.8
+      uses: actions/setup-python@v2
+      with:
+        python-version: 3.8
+    - name: Install tox and nox
+      run: python -m pip install tox nox
+
+    # Main check
+    - name: Check vendored packages
+      run: python -m tox -e "vendoring"
+
+    - name: Prepare dummy release
+      run: nox -s prepare-release -- 99.9
+
+    - name: Generate distributions for the dummy release
+      run: nox -s build-release -- 99.9
+
+  tests:
+    name: Tests / ${{ matrix.python }}
+    runs-on: macos-latest
+
+    needs: dev-tools
+
+    strategy:
+      fail-fast: false
+      matrix:
+        python: [2.7, 3.5, 3.6, 3.7, 3.8, 3.9]
+
+    steps:
+    # Caches
+    - name: pip cache
+      uses: actions/cache@v1
+      with:
+        path: ~/.cache/pip
+        key: ${{ runner.os }}-pip-${{ hashFiles('tools/requirements/tests.txt') }}-${{ hashFiles('tools/requirements/docs.txt') }}-${{ hashFiles('tox.ini') }}
+        restore-keys: |
+          ${{ runner.os }}-pip-
+          ${{ runner.os }}-
+    # Setup
+    - uses: actions/checkout@v2
+    - uses: actions/setup-python@v2
+      with:
+        python-version: ${{ matrix.python }}
+
+    - name: Install tox
+      run: python -m pip install tox 'virtualenv<20'
+
+    # Main check
+    - name: Run unit tests
+      run: >-
+        python -m tox -e py --
+        -m unit
+        --verbose
+        --numprocesses auto
+
+    - name: Run integration tests
+      run: >-
+        python -m tox -e py --
+        -m integration
+        --verbose
+        --numprocesses auto
+        --durations=5