diff --git a/CMakeLists.txt b/CMakeLists.txt
index d11228ae5..5563042df 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -39,6 +39,8 @@ target_include_directories(ClawsMail PRIVATE ${CMAKE_SOURCE_DIR}/src/common)
 target_include_directories(ClawsMail PRIVATE ${CMAKE_SOURCE_DIR}/src/etpan)
 target_include_directories(ClawsMail PRIVATE ${CMAKE_SOURCE_DIR}/src/gtk)
 
+target_compile_definitions(ClawsMail PRIVATE -DUSE_GPGME)
+
 
 ## GLib 2.0 ##