diff --git a/gnu/local.mk b/gnu/local.mk
index e5745ba9e6..0c40d6c0b8 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -613,6 +613,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/ceph-skip-unittest_blockdev.patch	\
   %D%/packages/patches/chmlib-inttypes.patch			\
   %D%/packages/patches/clang-3.5-libc-search-path.patch		\
+  %D%/packages/patches/clang-3.5-libsanitizer-ustat-fix.patch	\
   %D%/packages/patches/clang-3.8-libc-search-path.patch		\
   %D%/packages/patches/clang-6.0-libc-search-path.patch		\
   %D%/packages/patches/clang-runtime-asan-build-fixes.patch	\
diff --git a/gnu/packages/llvm.scm b/gnu/packages/llvm.scm
index d0791d00cc..aef24b3bac 100644
--- a/gnu/packages/llvm.scm
+++ b/gnu/packages/llvm.scm
@@ -7,6 +7,7 @@
 ;;; Copyright © 2017 Roel Janssen <roel@gnu.org>
 ;;; Copyright © 2018 Marius Bakke <mbakke@fastmail.com>
 ;;; Copyright © 2018 Tobias Geerinckx-Rice <me@tobias.gr>
+;;; Copyright © 2018 Efraim Flashner <efraim@flashner.co.il>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -270,7 +271,8 @@ code analysis tools.")
    llvm-3.9.1
    "16gc2gdmp5c800qvydrdhsp0bzb97s8wrakl6i8a4lgslnqnf2fk"
    '("clang-runtime-asan-build-fixes.patch"
-     "clang-runtime-esan-build-fixes.patch")))
+     "clang-runtime-esan-build-fixes.patch"
+     "clang-3.5-libsantitizer-ustat-fix.patch")))
 
 (define-public clang-3.9.1
   (clang-from-llvm llvm-3.9.1 clang-runtime-3.9.1
@@ -294,7 +296,8 @@ code analysis tools.")
   (clang-runtime-from-llvm
    llvm-3.8
    "0p0y85c7izndbpg2l816z7z7558axq11d5pwkm4h11sdw7d13w0d"
-   '("clang-runtime-asan-build-fixes.patch")))
+   '("clang-runtime-asan-build-fixes.patch"
+     "clang-3.5-libsantitizer-ustat-fix.patch")))
 
 (define-public clang-3.8
   (clang-from-llvm llvm-3.8 clang-runtime-3.8
@@ -317,7 +320,8 @@ code analysis tools.")
   (clang-runtime-from-llvm
    llvm-3.7
    "10c1mz2q4bdq9bqfgr3dirc6hz1h3sq8573srd5q5lr7m7j6jiwx"
-   '("clang-runtime-asan-build-fixes.patch")))
+   '("clang-runtime-asan-build-fixes.patch"
+     "clang-3.5-libsantitizer-ustat-fix.patch")))
 
 (define-public clang-3.7
   (clang-from-llvm llvm-3.7 clang-runtime-3.7
diff --git a/gnu/packages/patches/clang-3.5-libsantitizer-ustat-fix.patch b/gnu/packages/patches/clang-3.5-libsantitizer-ustat-fix.patch
new file mode 100644
index 0000000000..cfb09a8ce3
--- /dev/null
+++ b/gnu/packages/patches/clang-3.5-libsantitizer-ustat-fix.patch
@@ -0,0 +1,46 @@
+From d9d97cac3702b99a00cd113de98c41eb535d47ed Mon Sep 17 00:00:00 2001
+From: Efraim Flashner <efraim@flashner.co.il>
+Date: Sun, 14 Oct 2018 12:11:30 +0300
+Subject: [PATCH] patch modified from the gcc patch series, also dealing with
+ ustat.
+
+---
+ .../sanitizer_platform_limits_posix.cc            | 15 +++++++++++++--
+ 1 file changed, 13 insertions(+), 2 deletions(-)
+
+diff --git a/lib/sanitizer_common/sanitizer_platform_limits_posix.cc b/lib/sanitizer_common/sanitizer_platform_limits_posix.cc
+index 29fea6e..570b9a5 100644
+--- a/lib/sanitizer_common/sanitizer_platform_limits_posix.cc
++++ b/lib/sanitizer_common/sanitizer_platform_limits_posix.cc
+@@ -129,7 +129,6 @@
+ #include <sys/statvfs.h>
+ #include <sys/timex.h>
+ #include <sys/user.h>
+-#include <sys/ustat.h>
+ #include <linux/cyclades.h>
+ #include <linux/if_eql.h>
+ #include <linux/if_plip.h>
+@@ -222,7 +221,19 @@ namespace __sanitizer {
+ #endif  // SANITIZER_LINUX || SANITIZER_FREEBSD
+ 
+ #if SANITIZER_LINUX && !SANITIZER_ANDROID
+-  unsigned struct_ustat_sz = sizeof(struct ustat);
++  // Use pre-computed size of struct ustat to avoid <sys/ustat.h> which
++  // has been removed from glibc 2.28.
++#if defined(__aarch64__) || defined(__s390x__) || defined (__mips64) \
++  || defined(__powerpc64__) || defined(__arch64__) || defined(__sparcv9) \
++  || defined(__x86_64__)
++#define SIZEOF_STRUCT_USTAT 32
++#elif defined(__arm__) || defined(__i386__) || defined(__mips__) \
++  || defined(__powerpc__) || defined(__s390__)
++#define SIZEOF_STRUCT_USTAT 20
++#else
++#error Unknown size of struct ustat
++#endif
++  unsigned struct_ustat_sz = SIZEOF_STRUCT_USTAT;
+   unsigned struct_rlimit64_sz = sizeof(struct rlimit64);
+   unsigned struct_statvfs64_sz = sizeof(struct statvfs64);
+ #endif  // SANITIZER_LINUX && !SANITIZER_ANDROID
+-- 
+2.19.1
+