diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 764cf8c939..5e98aea91f 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -4063,7 +4063,7 @@ predicts the locations of structural units in the sequences.")
 (define-public proteinortho
   (package
     (name "proteinortho")
-    (version "5.16")
+    (version "5.16b")
     (source
      (origin
       (method url-fetch)
@@ -4073,7 +4073,7 @@ predicts the locations of structural units in the sequences.")
         version "_src.tar.gz"))
       (sha256
        (base32
-        "0z4f5cg0cs8ai62hfvp4q6w66q2phcc55nhs4xj5cyhxxivjv2ai"))))
+        "1wl0dawpssqwfjvr651r4wlww8hhjin8nba6xh71ks7sbypx886j"))))
     (build-system gnu-build-system)
     (arguments
      `(#:test-target "test"