diff --git a/biology/vsearch/Makefile b/biology/vsearch/Makefile
index 721dfc80a406..c35c0e74180d 100644
--- a/biology/vsearch/Makefile
+++ b/biology/vsearch/Makefile
@@ -2,7 +2,7 @@
 
 PORTNAME=		vsearch
 DISTVERSIONPREFIX=	v
-DISTVERSION=		2.14.2
+DISTVERSION=		2.15.0
 CATEGORIES=		biology
 
 MAINTAINER=	jwb@FreeBSD.org
diff --git a/biology/vsearch/distinfo b/biology/vsearch/distinfo
index acb0c97d6a21..0daf5be264be 100644
--- a/biology/vsearch/distinfo
+++ b/biology/vsearch/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1581796821
-SHA256 (torognes-vsearch-v2.14.2_GH0.tar.gz) = 4eba7b28e23580a8874b528e5a7345938c8adfbf3fe7eccfe90b352dfc8a3506
-SIZE (torognes-vsearch-v2.14.2_GH0.tar.gz) = 239518
+TIMESTAMP = 1592661073
+SHA256 (torognes-vsearch-v2.15.0_GH0.tar.gz) = c5d6eca1e4bf0c6e28221356b806c1d2322b51c39f40888636ab094c4df2e231
+SIZE (torognes-vsearch-v2.15.0_GH0.tar.gz) = 241192